ORAI3 抗体 (N-Term)
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Quick Overview for ORAI3 抗体 (N-Term) (ABIN500425)
抗原
See all ORAI3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody detects ORAI3 at N-term. It is predicted to have no cross-reactivity to ORAI1 or ORAI2.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Peptide affinity chromatography
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免疫原
- ORAI3 antibody was raised against a 15 amino acid peptide from near the amino terminus of human ORAI3.
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亚型
- IgG
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anti-ORAI Calcium Release-Activated Calcium Modulator 3 (ORAI3) antibody
ORAI3 适用: 人 WB 宿主: 兔 Monoclonal 25GB4720 unconjugated Recombinant Antibody
anti-ORAI Calcium Release-Activated Calcium Modulator 3 (ORAI3) (AA 1-30) antibodyORAI3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-ORAI Calcium Release-Activated Calcium Modulator 3 (ORAI3) (C-Term) antibodyORAI3 适用: 人, 小鼠 WB, IHC (p), IF, EIA 宿主: 兔 Polyclonal unconjugated
anti-ORAI Calcium Release-Activated Calcium Modulator 3 (ORAI3) (C-Term) antibodyORAI3 适用: 人, 大鼠 WB, IHC (p), EIA 宿主: 小鼠 Monoclonal 2H2G9 unconjugated
anti-ORAI Calcium Release-Activated Calcium Modulator 3 (ORAI3) (C-Term) antibodyORAI3 适用: 人, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western blot: 1 - 2 μg/mL. Immunoflourescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- ORAI3 (ORAI Calcium Release-Activated Calcium Modulator 3 (ORAI3))
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别名
- ORAI3
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背景
- Antigen stimulation of immune cells triggers Ca++ entry through Ca++ release-activated Ca++ (CRAC) channels. ORAI3 is one of two mammalian homologs to ORAI1, a recently identified four-transmembrane spanning protein that is an essential component of CRAC. All three homologs have been shown to function as Ca++ plasma membrane channels gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor. However, ORAI3 channels failed to produce detectable Ca++ selective currents in cells co-transfected with ORAI3 and STIM1, indicating that ORAI3 channels undergo a lesser degree of depotentiation than ORAI1 or ORAI2. Na+ currents through ORAI1, 2 and 3 channels were equally inhibited by extracellular Ca++, indicating that each have similar affinities for Ca++ within the selectivity filter.Synonyms: ORAI-3, TMEM142C, Transmembrane Protein 142C
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基因ID
- 93129
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UniProt
- Q9BRQ5
抗原
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