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Stathmin 1 抗体 (C-Term)

This anti-Stathmin 1 antibody is a 兔 多克隆 antibody detecting Stathmin 1 in WB, IHC (p) 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN500415
发货至: 中国

Quick Overview for Stathmin 1 抗体 (C-Term) (ABIN500415)

抗原

See all Stathmin 1 (STMN1) 抗体
Stathmin 1 (STMN1)

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This Stathmin 1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
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    C-Term

    特异性

    This antibody detects Stathmin / STMN1 at C-term.

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse

    纯化方法

    Peptide affinity chromatography

    免疫原

    Op18 antibody was raised against a 20 amino acid peptide from near the carboxy terminus of human op18.

    亚型

    IgG
  • 应用备注

    ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    Stathmin 1 (STMN1)

    别名

    Stathmin / STMN1

    背景

    Op18 belongs to the stathmin family of genes and encodes a ubiquitous cytosolic phosphoprotein that may function as an intracellular relay integrating several signaling pathways such as those involved in cell proliferation and differentiation. Op18 has also been shown to be involved in the regulation of the microtubule filament system by destabilizing microtubules, thereby preventing assembly and promoting the disassembly of microtubules. More recently, op18 has been implicated as a potential target of the ASK1-p38 MAP kinase cascade, suggesting that the ASK1-p38 cascade may regulate microtubule dynamics through op18. Op18 is highly expressed in a wide variety of human malignancies, including leukemia, prostate cancer, ovarian carcinoma, and breast carcinoma, suggesting that op18 may be an ideal target for anti-cancer therapeutics.Synonyms: LAP18, Leukemia-associated phosphoprotein p18, Metablastin, OP18, Oncoprotein 18, Op18, Phosphoprotein p19, Prosolin, Protein Pr22, pp17, pp19

    基因ID

    3925

    UniProt

    P16949

    途径

    MAPK Pathway, Microtubule Dynamics
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