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MICA 抗体 (C-Term)

The 兔 多克隆 anti-MICA antibody (ABIN500280) specifically detects MICA in WB, IHC (p) 和 EIA. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN500280
发货至: 中国
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Quick Overview for MICA 抗体 (C-Term) (ABIN500280)

抗原

See all MICA 抗体
MICA (MHC Class I Polypeptide-Related Sequence A (MICA))

适用

  • 102
  • 18
  • 14
  • 11
  • 7
  • 4
  • 2
  • 1
人, 小鼠

宿主

  • 44
  • 43
  • 17

克隆类型

  • 64
  • 37
  • 2
多克隆

标记

  • 63
  • 11
  • 8
  • 7
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This MICA antibody is un-conjugated

应用范围

  • 50
  • 42
  • 39
  • 21
  • 20
  • 13
  • 9
  • 8
  • 6
  • 6
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 8
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    特异性

    This antibody detects MICA.

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse

    纯化方法

    Peptide affinity chromatography

    免疫原

    MICA antibody was raised against a 16 amino acid peptide from near the carboxy terminus of human MICA.

    亚型

    IgG
  • 应用备注

    ELISA. Western blot. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    MICA (MHC Class I Polypeptide-Related Sequence A (MICA))

    别名

    MICA

    背景

    Major histocompatibility complex (MHC) class I proteins are ubiquitously expressed and mediate the recognition of intracellular antigens by cytotoxic T cells. A related family, termed the MHC class I chain-related (MIC) proteins are recognized by NKG2D, a receptor on NK and T cells, and promote anti-tumor activity. MICA, a member of the MIC family, is widely expressed on many tumors, and it is the MICA/NKG2D interaction that is thought to stimulate the anti-tumor reactivity by T lymphocytes. Both MICA and MICB mRNA are widely expressed in normal tissues, with MICA being present in virtually every tissue except the nervous system, suggesting that MIC protein expression may only be one component of the anti-tumor activity of the immune system.Synonyms: MHC class I polypeptide-related sequence A, MIC-A, PERB11.1

    基因ID

    4276

    NCBI登录号

    NP_000238

    UniProt

    Q29983

    途径

    Activation of Innate immune Response, Transition Metal Ion Homeostasis, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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