BIRC7 抗体 (AA 264-280)
Quick Overview for BIRC7 抗体 (AA 264-280) (ABIN500182)
抗原
See all BIRC7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 264-280
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特异性
- This antibody detects BIRC7 / LIVIN.
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交叉反应 （详细）
- Species reactivity (tested):Human
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纯化方法
- Peptide affinity chromatography
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免疫原
- Livin antibody was raised with a synthetic peptide corresponding to amino acids 264 to 280 of the short form and 281 to 298 of the long form of human Livin (1,3). .Remarks: The sequence is identical between a and b forms of the Livin proteins.
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亚型
- IgG
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anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (AA 101-200) antibody
BIRC7 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) antibodyBIRC7 适用: 人 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (C-Term) antibodyVerified BIRC7 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (AA 264-280) antibodyBIRC7 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (AA 1-90) antibodyBIRC7 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 3H1 unconjugated
anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (AA 87-298) antibodyBIRC7 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (C-Term) antibodyBIRC7 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (AA 1-265) antibodyBIRC7 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (C-Term) antibodyBIRC7 适用: 人, Cow, 犬, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (AA 1-298) antibodyBIRC7 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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ELISA. Western blot: 2 to 4 μg/mL. Human Raji cell lysate can be used as a positive control and aband at 33 kDa can be detected. A lower but much weaker band at 30 kDa was detected inRaji cell lysate, which may represent the short form of Livin. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))
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别名
- BIRC7 / LIVIN
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背景
- Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family that binds to and inhibits cell death proteases. A novel member in the IAP protein family was recently identified and designated Livin and KIAP for kidney IAP (1,2). Livin/XIAP contains a single baculoviral IAP repeat (BIR) domain and a RING finger domain and has two isoforms termed Livin-a and Livin-b (1,3). Transfection of Livin in cells resulted in protection from apoptosis induced by FADD, BAX, RIP, RIP3 and DR6 (1). Livin has direct interaction with several caspases including caspase-3, -7, and -9. Livin inhibits the activation of caspase-9 induced by Apaf-1, cytochrome c, and dATP. The two isoforms of Livin appear to have different functions and tissue distributions.Synonyms: Baculoviral IAP repeat-containing protein 7, KIAP, Kidney inhibitor of apoptosis protein, Livin, MLIAP, Melanoma inhibitor of apoptosis protein, RING finger protein 50, RNF50
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基因ID
- 79444
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NCBI登录号
- NP_071444
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UniProt
- Q96CA5
抗原
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