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Caspase 2 抗体 (N-Term)

This anti-Caspase 2 antibody is a 兔 多克隆 antibody detecting Caspase 2 in WB, IF 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN499559
发货至: 中国

Quick Overview for Caspase 2 抗体 (N-Term) (ABIN499559)

抗原

See all Caspase 2 (CASP2) 抗体
Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))

适用

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人, 小鼠

宿主

  • 112
  • 5
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克隆类型

  • 96
  • 24
多克隆

标记

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This Caspase 2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 抗原表位

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    N-Term

    特异性

    Caspase-2 antibody was raised against a 16 amino acid peptide from the amino-terminus of human Caspase-2.

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    Murine Casp-2 / ICH-1 / Nedd2 (N-Terminus) Peptide

    亚型

    IgG
  • 应用备注

    ELISA. Western Blot: Caspase-2 antibody can be used for the detection of caspase-2 at 1 μg/mL. Depending on cell lines or tissues used, other cleavage products may be observed. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))

    别名

    Caspase-2

    背景

    Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens (reviewed in 1 and 2). Members of this subfamily include caspase-1, -4, -5, and -12 and can activate proinflammatory cytokines such as IL-1beta and IL-18 (3,4). Although phylogenetically similar to this subfamily, Caspase-2 is thought to be involved in stress-induced apoptosis (5). Caspase-2 has two major isoforms, overexpression on the long form results in apoptosis while that of the short form suppresses cell death (6).Synonyms: CASP-2, CASP2, ICH-1 protease, ICH1, NEDD2, Neural precursor cell expressed developmentally down-regulated protein 2

    基因ID

    835

    UniProt

    P42575

    途径

    Apoptosis, Caspase Cascade in Apoptosis, Neurotrophin Signaling Pathway
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