Caspase 12 抗体 (N-Term)
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- 抗原 See all Caspase 12 (CASP12) 抗体
- Caspase 12 (CASP12) (Caspase 12 (Gene/pseudogene) (CASP12))
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抗原表位
- N-Term
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Caspase 12 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 特异性
- Caspase-12 antibody was raised against a peptide corresponding to amino acids 2 to 17 of murine caspase-12.
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- Mouse Caspase-12 (N-Terminus) Peptide
- 亚型
- IgG
- Top Product
- Discover our top product CASP12 Primary Antibody
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anti-Caspase 12 (Gene/pseudogene) (CASP12) (AA 201-300) antibody
CASP12 适用: 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Caspase 12 (Gene/pseudogene) (CASP12) (AA 1-413) antibodyCASP12 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 12 (Gene/pseudogene) (CASP12) (AA 1-244) antibodyCASP12 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 12 (Gene/pseudogene) (CASP12) (AA 165-193) antibodyCASP12 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Caspase 12 (Gene/pseudogene) (CASP12) (AA 71-84) antibodyCASP12 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Caspase 12 (Gene/pseudogene) (CASP12) (AA 61-282) antibodyCASP12 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase 12 (Gene/pseudogene) (CASP12) (AA 1-100) antibodyCASP12 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase 12 (Gene/pseudogene) (CASP12) (AA 100-116) antibodyCASP12 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Caspase 12 (Gene/pseudogene) (CASP12) (AA 165-193) antibodyCASP12 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB31705 unconjugated
anti-Caspase 12 (Gene/pseudogene) (CASP12) (AA 95-318), (N-Term) antibodyCASP12 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), IP 宿主: 大鼠 Monoclonal 14F7 unconjugated
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- 应用备注
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ELISA. Western Blot: Caspase-12 antibody can be used for detection of caspase-12 at 0.5 to 1 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 缓冲液
- PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C.
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- 抗原
- Caspase 12 (CASP12) (Caspase 12 (Gene/pseudogene) (CASP12))
- 别名
- Caspase-12 (CASP12 产品)
- 背景
- Three distinct signaling pathways lead to programmed cell death (apoptosis). The death receptor and mitochondrion pathways are the mains, in which the key apoptotic proteases capase-8 and caspase-9, respectively, are involved. The endoplasmic reticulum (ER) stress is the third apoptotic pathway and caspase-12 is involved (1,2). Caspase-12 is localized to the ER but not to cytoplasm or mitochondrion. Caspase-12 is activated by ER stress, including disruption of ER calcium homeostasis, and mediates ER stress-induced apoptosis. Caspase-12 is co-localized to the ER with several proteins that are involved in Alzheimer\'s disease including g-secretase presenilin and b-amyloid precursor protein (APP). Caspase-12 mediates cytotoxicity induced by amyloid-b. Caspase-12 is ubiquitously expressed in mouse tissues (1).Synonyms: CASP-12, CASP12, Inactive caspase-12
- 基因ID
- 100044205
- UniProt
- O08736
- 途径
- Apoptosis, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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