CARD10 抗体
Quick Overview for CARD10 抗体 (ABIN499533)
抗原
See all CARD10 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- CARD10 antibody was raised against a synthetic peptide corresponding to 14 amino acids at the C-terminus of human CARD10.
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纯化方法
- Immunoaffinity
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免疫原
- Murine CARD10 / Caspase recuitment domain family 10 / CARMA3 / Bimp1 Peptide
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亚型
- IgG
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anti-Caspase Recruitment Domain Family, Member 10 (CARD10) (AA 863-1032) antibody
CARD10 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 10 (CARD10) (N-Term) antibodyCARD10 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 10 (CARD10) antibodyCARD10 适用: 人, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 10 (CARD10) (AA 341-600) antibodyCARD10 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 10 (CARD10) (AA 481-530) antibodyCARD10 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 10 (CARD10) (Internal Region) antibodyCARD10 适用: 人, 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western BLot: CARD10 antibody can be used for detection of CARD10 at 5 - 10 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- CARD10 (Caspase Recruitment Domain Family, Member 10 (CARD10))
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别名
- CARD10 / CARMA3
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背景
- Apoptosis is related to many diseases and development. Cell death signals are transduced by death domain (DD), death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. CARD containing proteins include some caspases, Apaf-1, CARD4, IAPs, RICK, ARC, RAIDD, Bcl-10, and ASC. A novel CARD-containing protein was recently identified and designated CARD10 (1). This protein belongs to the membrane-associated guanylate kinase-like (MAGUK) family of proteins that can function as molecular scaffolds that assist assembly of signal transduction molecules (2). CARD 10 interacts with Bcl-10, a Bcl protein that promotes apoptosis, caspase-9 maturation and activation of NF-kappaB (1,3). CARD 10 and the related protein CARMA1 also associate with NEMO, the regulatory subunit of the IkappaK complex (4), demonstrating its importance in the regulation of NF-kappaB transcription factor activation.Synonyms: CARD-containing MAGUK protein 3, Caspase recruitment domain-containing protein 10
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基因ID
- 29775
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UniProt
- F1BA47
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途径
- S100 Proteins
抗原
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