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BTK 抗体 (N-Term)

BTK 适用: 人, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499507
发货至: 中国
  • 抗原 See all BTK 抗体
    BTK (Bruton Agammaglobulinemia tyrosine Kinase (BTK))
    抗原表位
    • 37
    • 16
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    N-Term
    适用
    • 130
    • 89
    • 79
    • 14
    • 6
    • 4
    • 2
    人, 小鼠
    宿主
    • 152
    • 9
    克隆类型
    • 142
    • 20
    多克隆
    标记
    • 61
    • 14
    • 10
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    • 8
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    • 8
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    This BTK antibody is un-conjugated
    应用范围
    • 103
    • 64
    • 40
    • 40
    • 37
    • 16
    • 14
    • 13
    • 10
    • 10
    • 8
    • 3
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    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    特异性
    BTK antibody was raised against a synthetic peptide corresponding to 16 amino acids near the amino-terminus of human BTK.
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    Human BTK / ATK / BPK (N-Terminus) Peptide
    亚型
    IgG
    Top Product
    Discover our top product BTK Primary Antibody
  • 应用备注
    ELISA. Western Blot: BTK antibody can be used for the detection of BTK at 0.5 to 1 μg/mL. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    BTK (Bruton Agammaglobulinemia tyrosine Kinase (BTK))
    别名
    BTK (BTK 产品)
    别名
    BTK antibody, atk antibody, bpk antibody, xla antibody, imd1 antibody, agmx1 antibody, psctk1 antibody, AGMX1 antibody, AT antibody, ATK antibody, BPK antibody, IMD1 antibody, PSCTK1 antibody, XLA antibody, AI528679 antibody, xid antibody, Bruton tyrosine kinase antibody, Bruton agammaglobulinemia tyrosine kinase antibody, BTK antibody, btk antibody, Btk antibody
    背景
    Bruton's tyrosine kinase (BTK) was initially identified as a member of the src family for protein-tyrosine kinases that was involved in X-linked aγ-globulinaemia (1), and has since been shown to involved in a number of signaling pathways in hemapoietic lineage (reviewed in 2). It has recently been shown to interact with members of the toll-like receptor (TLR) family such as TLR4, 6, 8, and 9 (3). The TLRs are critical molecules in both the innate and adaptive immunity and can recognize diverse microbial pathogens (reviewed in 4). BTK has also been shown to interact with key proteins involved in TLR4 signal transduction such as MyD88, TIRAP, and IRAK, but not TRAF-6, suggesting that BTK is involved in lipopolysaccharide signal transduction (3).Synonyms: AGMX1, ATK, Agammaglobulinaemia tyrosine kinase, B-cell progenitor kinase, BPK, Bruton tyrosine kinase, Tyrosine-protein kinase BTK
    基因ID
    695
    UniProt
    Q06187
    途径
    Fc-epsilon Receptor Signaling Pathway, Hormone Transport, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, BCR Signaling
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