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BID 抗体 (C-Term)

BID 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499461
发货至: 中国
  • 抗原 See all BID 抗体
    BID (BH3 Interacting Domain Death Agonist (BID))
    抗原表位
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    C-Term
    适用
    • 124
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    人, 小鼠
    宿主
    • 134
    • 19
    • 2
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    克隆类型
    • 125
    • 31
    多克隆
    标记
    • 86
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    This BID antibody is un-conjugated
    应用范围
    • 139
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    Bid antibody was raised against a peptide corresponding to 14 amino acids near the carboxy-terminus of human Bid.
    纯化方法
    Ion exchange chromatography
    免疫原
    Human Bid (C-Terminus) Peptide
    亚型
    IgG
    Top Product
    Discover our top product BID Primary Antibody
  • 应用备注
    ELISA. Western Blot: Bid antibody can be used for detection of Bid at 0.5 to 1 μg/mLImmunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    BID (BH3 Interacting Domain Death Agonist (BID))
    别名
    BID (BID 产品)
    别名
    FP497 antibody, 2700049M22Rik antibody, AI875481 antibody, AU022477 antibody, BID antibody, bid antibody, si:ch211-238n5.6 antibody, fp497 antibody, xbid antibody, DKFZp469E066 antibody, BH3 interacting domain death agonist antibody, BH3 interacting domain death agonist S homeolog antibody, BID antibody, Bid antibody, bida antibody, bid.S antibody, bid antibody
    背景
    Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer (reviewed in 1). The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death (reviewed in 2 and 3). Bid, a pro-apoptotic Bcl-2 family member, is cleaved by caspase-8 in response to apoptotic signals (4,5), exposing the Bcl-2 homology 3 (BH3) domain which is normally buried in the full-length protein (6). The cleaved complex is myris-toylated and translocated to the mitochondrial membrane where it may induce mitochondrial Bax and Bak to oligomerize (7,8).Synonyms: BH3-interacting domain death agonist, p22 BID
    基因ID
    637
    UniProt
    P55957
    途径
    Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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