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BID 抗体 (C-Term)

This anti-BID antibody is a 兔 多克隆 antibody detecting BID in WB, IHC (p) 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN499461
发货至: 中国
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Quick Overview for BID 抗体 (C-Term) (ABIN499461)

抗原

See all BID 抗体
BID (BH3 Interacting Domain Death Agonist (BID))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This BID antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
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    C-Term

    特异性

    Bid antibody was raised against a peptide corresponding to 14 amino acids near the carboxy-terminus of human Bid.

    纯化方法

    Ion exchange chromatography

    免疫原

    Human Bid (C-Terminus) Peptide

    亚型

    IgG
  • 应用备注

    ELISA. Western Blot: Bid antibody can be used for detection of Bid at 0.5 to 1 μg/mLImmunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    BID (BH3 Interacting Domain Death Agonist (BID))

    别名

    BID

    背景

    Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer (reviewed in 1). The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death (reviewed in 2 and 3). Bid, a pro-apoptotic Bcl-2 family member, is cleaved by caspase-8 in response to apoptotic signals (4,5), exposing the Bcl-2 homology 3 (BH3) domain which is normally buried in the full-length protein (6). The cleaved complex is myris-toylated and translocated to the mitochondrial membrane where it may induce mitochondrial Bax and Bak to oligomerize (7,8).Synonyms: BH3-interacting domain death agonist, p22 BID

    基因ID

    637

    UniProt

    P55957

    途径

    Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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