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PYCARD 抗体

PYCARD 适用: 人 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499343
发货至: 中国
  • 抗原 See all PYCARD 抗体
    PYCARD (PYD and CARD Domain Containing (PYCARD))
    适用
    • 57
    • 10
    • 9
    • 1
    • 1
    • 1
    宿主
    • 48
    • 7
    • 3
    克隆类型
    • 46
    • 12
    多克隆
    标记
    • 33
    • 4
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    This PYCARD antibody is un-conjugated
    应用范围
    • 40
    • 23
    • 15
    • 13
    • 5
    • 5
    • 4
    • 4
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    特异性
    ASC antibody was raised against a synthetic peptide corresponding to amino acids 182 to 195 of human ASC .
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    Human ASC Peptide
    亚型
    IgG
    Top Product
    Discover our top product PYCARD Primary Antibody
  • 应用备注
    ELISA. Western Blot: ASC antibody can be used for detection of ASC/TMS1 at 1 μg/mL. Anapproximately 25 kDa band can be detected. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    PYCARD (PYD and CARD Domain Containing (PYCARD))
    别名
    CARD5 / PYCARD / ASC (PYCARD 产品)
    别名
    ASC antibody, CARD5 antibody, TMS antibody, TMS-1 antibody, TMS1 antibody, 9130417A21Rik antibody, Asc antibody, TNS1 antibody, masc antibody, asc1 antibody, zAsc antibody, zgc:109874 antibody, PYD and CARD domain containing antibody, PYCARD antibody, Pycard antibody, pycard antibody
    背景
    Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. CARD containing cell death regulators include RAIDD, RICK, BCL10, Apaf-1, ARC, caspase-9, and caspase-2. A novel CARD domain containing protein was recently identified in human and mouse and designated ASC and TMS1 (1-3). Ectopic expression of ASC/TMS1 induced apoptosis through activation of caspase-9 and inhibited the survival of human breast cancer cells (3,4). Overexpression of ASC/TMS1 induced DNA fragmentation (4). ASC/TMS1 is expressed in a variety of human and mouse tissues (1, 2)Synonyms: Caspase recruitment domain-containing protein 5, PYD and CARD domain-containing protein, TMS1, Target of methylation-induced silencing 1, poptosis-associated speck-like protein containing a CARD
    基因ID
    29108
    UniProt
    Q9ULZ3
    途径
    Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation, Inflammasome
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