Ephrin B2 抗体 (Internal Region)
Our Local Distributor
北京 101111
Quick Overview for Ephrin B2 抗体 (Internal Region) (ABIN499146)
抗原
See all Ephrin B2 (EFNB2) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Internal Region
-
序列
- CPKVDSKTVG QYE
-
特异性
- Recognizes EFNB2
-
交叉反应 （详细）
-
Species reactivity (expected):Canine, Bovine, Pig.
Species reactivity (tested):Human, Mouse, Rat. -
纯化方法
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
-
免疫原
- Peptide with sequence from the internal region of the protein sequence according to NP_004084.1. Genename: EFNB2
-
-
anti-Ephrin B2 (EFNB2) (C-Term) antibody
EFNB2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ephrin B2 (EFNB2) (AA 28-229) antibodyEFNB2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ephrin B2 (EFNB2) antibodyKD Validated EFNB2 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2345 unconjugated Recombinant Antibody
anti-Ephrin B2 (EFNB2) (AA 157-186) antibodyEFNB2 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB31411 unconjugated
anti-Ephrin B2 (EFNB2) antibodyEFNB2 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ephrin B2 (EFNB2) antibodyEFNB2 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Ephrin B2 (EFNB2) (AA 28-127) antibodyEFNB2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Ephrin B2 (EFNB2) (pTyr330) antibodyEFNB2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ephrin B2 (EFNB2) antibodyEFNB2 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Ephrin B2 (EFNB2) (AA 28-229) antibodyEFNB2 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Peptide ELISA: Limit Dilution: 1/16000. Western blot: 0.1-0.3 μg/mL. This antibody detects a band of approx. 35 kDa band observed inHuman, Mouse and Rat Lung lysates.
-
限制
- 仅限研究用
-
-
-
浓度
- 0.5 mg/mL
-
缓冲液
- Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- Ephrin B2 (EFNB2)
-
别名
- Ephrin-B2
-
背景
- Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The ligand-activated form of EphB2, which belongs to the Tyr family of protein kinases, interacts with multiple proteins, including GTPase-activating protein (RASGAP)and also interacts with PRKCABP and GRIP1. This type I membrane protein is expressed in brain, heart, lung, kidney, placenta, pancreas, liver and skeletal muscle. It is preferentially expressed in fetal brain. Ephrin-B2 also binds EphA4, EphB1, EphB2, EphB3 and EphB4. Ephrin-B2 can be detected on monocytes, mesangial cells, CD34+ stem cells, bone marrow fibroblasts, activated melanocytes and melanoma cells, and pre-artery endothelial cells.Synonyms: EFNB2, EPH-related receptor tyrosine kinase ligand 5, EPLG5, HTK ligand, HTK-L, HTKL, LERK-5, LERK5
-
分子量
- 36.9kDa (NP_004084.1)
-
基因ID
- 1948
-
NCBI登录号
- NP_004084
-
UniProt
- P52799
-
途径
- RTK signaling, Regulation of Muscle Cell Differentiation
抗原
-
