C1S 抗体
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北京 101111
Quick Overview for C1S 抗体 (ABIN499051)
抗原
See all C1S 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of C1s protein. (region surrounding Lys583)
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- Affinity chromatography
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纯度
- > 95 % by SDS-PAGE
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anti-Complement Component 1, S Subcomponent (C1S) (AA 1-688) antibody
C1S 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 1, S Subcomponent (C1S) (C-Term) antibodyC1S 适用: 人 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 1, S Subcomponent (C1S) antibodyC1S 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 1, S Subcomponent (C1S) antibodyC1S 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 1, S Subcomponent (C1S) antibodyC1S 适用: 人 IHC, ELISA, IHC (p) 宿主: 山羊 Polyclonal unconjugated
anti-Complement Component 1, S Subcomponent (C1S) antibodyC1S 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 2F5 unconjugated
anti-Complement Component 1, S Subcomponent (C1S) (AA 1-688) antibodyC1S 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Complement Component 1, S Subcomponent (C1S) (AA 438-685) antibodyC1S 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 1, S Subcomponent (C1S) (Arg437), (cleaved) antibodyC1S 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 1, S Subcomponent (C1S) antibodyC1S 适用: 人, 大鼠, 小鼠, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2A8 unconjugated
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应用备注
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Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- C1S (Complement Component 1, S Subcomponent (C1S))
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别名
- C1s
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背景
- C1s proenzyme is a glycoprotein produced primarily by hepatocytes but also by other cells. The proenzyme is produced as a single chain polypeptide of 688 aa. Upon activation the peptide is cleaved between R437 and I438 giving the activated enzyme consisting of two disulfide-linked chains, A chain (52.2 kDa) and B chain (27.7 kDa). The Ca dependent catalytic subunit of the C1 complex (C1q, C1r, C1s) comprises of two C1s and two C1r molecules and this serine protease tetramer is responsible for the initial steps in the classical complement pathway, cleavage of C4 and C2.Synonyms: C1 esterase, Complement 1s, Complement C1s, Complement C1s subcomponent, Complement component 1 subcomponent s
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分子量
- approx. 77 kDa
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基因ID
- 716
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NCBI登录号
- NP_001725
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UniProt
- P09871
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途径
- Complement System
抗原
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