CAMK2B 抗体
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北京 101111
Quick Overview for CAMK2B 抗体 (ABIN499009)
抗原
See all CAMK2B 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of CaMKIIbeta/gamma/delta protein. (region surrounding Ser280)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography
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纯度
- > 95 % by SDS-PAGE
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anti-Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B) (AA 1-100) antibody
CAMK2B 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B) (pThr286) antibodyCAMK2B 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B) antibodyCAMK2B 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B) (AA 101-200) antibodyCAMK2B 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B) (AA 1-504) antibodyCAMK2B 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal S11 unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B) (AA 1-503) antibodyCAMK2B 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal S11 unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B) (AA 1-504) antibodyCAMK2B 适用: 人 WB, IHC (p), EIA 宿主: 小鼠 Monoclonal S11 unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B) (pThr287) antibodyCAMK2B 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B) (pThr286), (Thr287) antibodyCAMK2B 适用: 大鼠 WB, ELISA, IF, IP 宿主: 小鼠 Monoclonal 22B1 unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B) (AA 405-502) antibodyCAMK2B 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 6D6 unconjugated
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应用备注
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CAMK2B (Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B))
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别名
- CAMK2B
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背景
- The Ca2+/calmodulin-dependent protein kinases (CaM kinases) comprise a structurally related subfamily of serine/threonine kinases which include CaMKI, CaMKII and CaMKIV. CaMKII is an ubiquitously expressed serine/threonine protein kinase that is activated by Ca2+ and calmodulin (CaM) and has been implicated in regulation of the cell cycle and transcription. There are four CaMKII isozymes, designated alpha, beta, gamma and delta, which may or may not be coexpressed in the same tissue type. CaMKIV is stimulated by Ca2+ and CaM but also requires phosphorylation by a CaMK for full activation. Stimulation of the T cell receptor CD3 signaling complex with an anti-CD3 monoclonal antibody leads to a 10-40-fold increase in CaMKIV activity. An additional kinase, CaMKK, functions to activate CaMKI through the specific phosphorylation of the regulatory threonine residue at position 177.Synonyms: CAM2, CAMKB, CAMKIIb, CaM kinase II subunit beta, CaM-kinase II beta chain, CaMK-II subunit beta, Calcium/calmodulin-dependent protein kinase type II beta chain
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分子量
- approx. 50, 65 kDa
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基因ID
- 816
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NCBI登录号
- NP_001211
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UniProt
- Q13554
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途径
- WNT signaling, Interferon-gamma Pathway, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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