DAPK3 抗体
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北京 101111
Quick Overview for DAPK3 抗体 (ABIN498992)
抗原
See all DAPK3 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of ZIPkinase protein. (region surrounding Lys261)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography
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纯度
- > 95 % by SDS-PAGE
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anti-Death-Associated Protein Kinase 3 (DAPK3) (AA 1-100) antibody
DAPK3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Death-Associated Protein Kinase 3 (DAPK3) (AA 28-161) antibodyDAPK3 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 4H4C8 unconjugated
anti-Death-Associated Protein Kinase 3 (DAPK3) (N-Term) antibodyDAPK3 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Death-Associated Protein Kinase 3 (DAPK3) (Thr265) antibodyDAPK3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Death-Associated Protein Kinase 3 (DAPK3) (AA 283-401) antibodyDAPK3 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Death-Associated Protein Kinase 3 (DAPK3) (Thr265) antibodyDAPK3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Death-Associated Protein Kinase 3 (DAPK3) antibodyDAPK3 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB1515 unconjugated Recombinant Antibody
anti-Death-Associated Protein Kinase 3 (DAPK3) antibodyDAPK3 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB4795 unconjugated Recombinant Antibody
anti-Death-Associated Protein Kinase 3 (DAPK3) (pThr265) antibodyDAPK3 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Death-Associated Protein Kinase 3 (DAPK3) (AA 30-130) antibodyDAPK3 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- DAPK3 (Death-Associated Protein Kinase 3 (DAPK3))
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别名
- DAPK3 / ZIPK
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背景
- Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certainserine/threonine protein kinases, such as ASK1 and RIP, are mediators of apoptosis. A novel serine/threonine kinase that mediates apoptosis was recently identified and designated ZIP kinase. ZIP kinase contains an N terminal kinase domain and a C terminal leucine zipper structure and binds to ATF4 that is a member of ATF/CREBfamily. ZIP kinase has high sequence homology to DAP kinase (death associated protein kinase), which is a mediator of apoptosis induced by gamma interferon. Overexpression of ZIP kinase induces apoptosis. ZIP and DAP kinases represent a novel kinase family, which mediates apoptosis through their catalytic activities. The messenger RNA was ubiquitously expressed in various tissues.Synonyms: DAP kinase 3, DAP-like kinase, DLK, Death-associated protein kinase 3, ZIP-kinase
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分子量
- approx. 52 kDa
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基因ID
- 1613
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NCBI登录号
- NP_001339
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UniProt
- O43293
抗原
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