SERPINB2 抗体
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北京 101111
Quick Overview for SERPINB2 抗体 (ABIN498689)
抗原
See all SERPINB2 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of PAI-2 protein. (region surrounding Val307)
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- Affinity chromatography
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纯度
- > 95 % by SDS-PAGE
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anti-Plasminogen Activator Inhibitor 2 (SERPINB2) antibody
SERPINB2 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen Activator Inhibitor 2 (SERPINB2) (Center) antibodySERPINB2 适用: 人, 小鼠 WB, IP, ICC, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen Activator Inhibitor 2 (SERPINB2) (AA 154-408) antibodySERPINB2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal A10 unconjugated
anti-Plasminogen Activator Inhibitor 2 (SERPINB2) (AA 1-100) antibodySERPINB2 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 3A9 unconjugated
anti-Plasminogen Activator Inhibitor 2 (SERPINB2) antibodySERPINB2 适用: 人 IHC 宿主: 兔 Monoclonal HMV330 unconjugated Recombinant Antibody
anti-Plasminogen Activator Inhibitor 2 (SERPINB2) (AA 116-144) antibodySERPINB2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB19097 unconjugated
anti-Plasminogen Activator Inhibitor 2 (SERPINB2) (AA 154-408) antibodySERPINB2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen Activator Inhibitor 2 (SERPINB2) (AA 1-415) antibodySERPINB2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Plasminogen Activator Inhibitor 2 (SERPINB2) (AA 293-389) antibodySERPINB2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen Activator Inhibitor 2 (SERPINB2) (Internal Region) antibodySERPINB2 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- SERPINB2 (Plasminogen Activator Inhibitor 2 (SERPINB2))
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别名
- SERPINB2 / PAI2
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物质类
- Amino Acid
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背景
- PAI-1 and PAI-2 (for plasminogen activator inhibitor-1 and -2) are members of the serpin serine proteinase inhibitor family. PAI-1 and PAI-2 have been shown to regulate uPA (urokinase-type plasminogen activator) and tPA (tissue plasminogen activator), resulting in the inhibition of proteolytic activity. Members of the serpin family generally complex with their target proteinases, then disassociate slowly into cleaved species that fold into stable inactive forms. PAI-1 can fold into the inactive state without cleavage, resulting in the latent form of PAI-1. Activity can be restored to the latent form of PAI-1 through denaturation and renaturation. PAI-2 occurs in secreted and cytosolic forms through facultative polypeptide translocation. uPA is a serine proteinase that is a member of the trypsin family. It is responsible for the cleavage of plasminogen at the Arg-Val bond to produce plasmin. uPA consists of two chains designated A and B. The A chain can be cleaved, resulting in low and high molecular mass forms of uPA.Synonyms: Monocyte Arg-serpin, PAI-2, PLANH2, Placental plasminogen activator inhibitor, Plasminogen activator inhibitor 2, Serpin B2, Urokinase inhibitor
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分子量
- approx. 45 kDa
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基因ID
- 5055
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NCBI登录号
- NP_001137290
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UniProt
- P05120
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途径
- Autophagy
抗原
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