ASCL1 抗体
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Quick Overview for ASCL1 抗体 (ABIN498679)
抗原
See all ASCL1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of ASCL1 protein. (region surrounding Glu158)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity Chromatography using epitope-specific immunogen.
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anti-Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1) (C-Term) antibody
ASCL1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1) (AA 186-236) antibodyASCL1 适用: 人, 小鼠 WB, IHC, ICC, IP, FACS 宿主: 兔 Monoclonal BLR164J unconjugated Recombinant Antibody
anti-Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1) (AA 151-236) antibodyASCL1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1) (AA 137-236) antibodyASCL1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3D3 unconjugated
anti-Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1) antibodyASCL1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1) (N-Term) antibodyASCL1 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 犬, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1) (AA 84-236) antibodyASCL1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1) (AA 137-236) antibodyASCL1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2D9 unconjugated
anti-Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1) (AA 48-97) antibodyASCL1 适用: 人, Cow, 豚鼠, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1) (AA 137-236) antibodyASCL1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Western Blot: 1/500-1/1000. Immunohistochemistry: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))
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别名
- ASCL1
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背景
- The mammalian homolog of the Drosophila protein achaetescute, ASCL1 (also known as ASH1) is a basic helix-loophelix transcription factor that is required for early development of the nervous system. Expressed in fetal brain, ASCL1 is essential for the proper development of autonomic neurons and for the survival of subsets of autonomic neurons. ASCL1 interaction with MEF-2A may regulate the expression of specific genes that are critical for the formation of distinct neuronal circuits within the central nervous system. The high level of ASCL1 expression in neuroendocrine tumors, such as medullary thyroid cancer, small cell lung cancer and lung cancer with neuroendocrine features may provide a useful marker for cancers with neuroendocrine features. Mapping to human chromosome 12, the ASCL1 gene contains a trinucleotide repeat region, making this locus a candidate for inherited disease.Synonyms: ASH1, Achaete-scute homolog 1, HASH1, MASH1
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分子量
- approx. 25 kDa
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基因ID
- 429
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NCBI登录号
- NP_004307
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UniProt
- P50553
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途径
- Dopaminergic Neurogenesis
抗原
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