PKC theta 抗体
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Quick Overview for PKC theta 抗体 (ABIN498658)
抗原
See all PKC theta (PRKCQ) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of PKC theta protein. (region surrounding asn670)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography
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纯度
- > 95 % by SDS-PAGE
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anti-Protein Kinase C, theta (PRKCQ) (pSer676) antibody
PRKCQ 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, theta (PRKCQ) (AA 380-634) antibodyPRKCQ 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, theta (PRKCQ) (AA 15-294) antibodyPRKCQ 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, theta (PRKCQ) (pThr538) antibodyPRKCQ 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, theta (PRKCQ) (C-Term) antibodyPRKCQ 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, theta (PRKCQ) antibodyPRKCQ 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB4105 unconjugated Recombinant Antibody
anti-Protein Kinase C, theta (PRKCQ) (pSer695) antibodyPRKCQ 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, theta (PRKCQ) (AA 318-348), (C-Term) antibodyPRKCQ 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB01242 unconjugated
anti-Protein Kinase C, theta (PRKCQ) (pSer676) antibodyPRKCQ 适用: 人, 大鼠, 小鼠, Cow, 犬, Pig, 猴 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, theta (PRKCQ) (AA 351-450) antibodyPRKCQ 适用: 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- PKC theta (PRKCQ) (Protein Kinase C, theta (PRKCQ))
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别名
- PRKCQ / PRKCT
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背景
- Members of the protein kinase C (PKC) family play a key regulatory role in variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes including conventional (c) PKC isoforms (alpha, betaI, betaII and gamma) and novel (n) PKC isoforms (delta, epsilon , zeta, eta and theta). Patterns of expression for each PKC isoform differs among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of nPKC delta and epsilonare independent of Ca++. On the other hand, nPKC and epsilon, as well as all of the cPKC members, possess phorbol esterbinding activities and kinase activities.Synonyms: PKC theta, PKC-theta, Protein kinase C theta type, Protein kinase C theta type, nPKC-theta
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分子量
- approx. 80 kDa
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基因ID
- 5588
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NCBI登录号
- NP_006248
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UniProt
- Q04759
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Thromboxane A2 Receptor Signaling
抗原
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