GJB1 抗体
Quick Overview for GJB1 抗体 (ABIN498543)
抗原
See all GJB1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of Connexin-32 protein. (region surrounding Leu115)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity Chromatography using epitope-specific immunogen
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anti-Gap Junction Protein, beta 1, 32kDa (GJB1) (C-Term) antibody
GJB1 适用: 人, 大鼠, 小鼠, 犬, Cow, 马, 兔, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, beta 1, 32kDa (GJB1) (Internal Region) antibodyGJB1 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, beta 1, 32kDa (GJB1) (AA 201-283) antibodyGJB1 适用: 人, 大鼠 ELISA, IHC (fro), IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, beta 1, 32kDa (GJB1) (AA 215-283) antibodyGJB1 适用: 人 IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, beta 1, 32kDa (GJB1) (C-Term) antibodyGJB1 适用: 人, 大鼠, 小鼠, 犬, Cow, 马, 兔, 猴, Pig, Bat, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, beta 1, 32kDa (GJB1) antibodyGJB1 适用: 人, 大鼠, 小鼠 IHC, StM 宿主: 小鼠 Monoclonal GJB1-1753 unconjugated
anti-Gap Junction Protein, beta 1, 32kDa (GJB1) antibodyGJB1 适用: 人, 大鼠, 小鼠 WB, IF, FACS, IHC (fro) 宿主: 小鼠 Monoclonal M12-13 unconjugated
anti-Gap Junction Protein, beta 1, 32kDa (GJB1) (C-Term) antibodyGJB1 适用: 人, 大鼠, 小鼠, 犬, Cow, 马, 兔, 猴, Pig, 豚鼠, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, beta 1, 32kDa (GJB1) (C-Term) antibodyGJB1 适用: 人, 大鼠, 小鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, beta 1, 32kDa (GJB1) (AA 75-174) antibodyGJB1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2B9 unconjugated
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应用备注
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Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- GJB1 (Gap Junction Protein, beta 1, 32kDa (GJB1))
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别名
- GJB1 / Cx32
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背景
- Gap junctions are aggregations of intercellular channels that directly connect the cytoplasm of adjacent cells. Gap junctions coordinate cellular and organ function in tissues and are involved in metabolic cooperation between cells, synchronization of cellular physiological activities, growth control and developmental regulation. The gap junction channels allow intercellular exchange of ions, nucleotides and small molecules between adjacent cells. Unlike other membrane channels, intercellular channels span two plasma membranes and require the contribution of hemichannels, called connexons, from both participating cells. These channels are permeate to molecules as large as 1 kD, and they have been detected in virtually every cell type in mammals, except mature skeletal muscle, spermatozoa and erythrocytes. Two connexons interact in the extracellular space to form the complete intercellular channel. Each connexon is composed of six similar or identical proteins, which are termed connexins. Connexins (Cx) are a multi-gene family of highly related proteins ranging between molecular weights of 26 and 70 kD. At least a dozen distinct connexin genes have been identified and many are expressed in a tissue-specific manner. Two distinct lineages have been identified in mammals. One termed class I or beta group to which Cx26, Cx30, Cx31, Cx31.1 and Cx32 belong, and the other termed class II or alpha group, represented by Cx33, Cx37, Cx40, Cx43 and Cx46.Synonyms: Connexin-32, GAP junction 28 kDa liver protein, Gap junction beta-1 protein
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分子量
- approx. 32 kDa
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基因ID
- 2705
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NCBI登录号
- NP_000157
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UniProt
- P08034
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途径
- Cell-Cell Junction Organization
抗原
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