IL12A 抗体
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北京 101111
Quick Overview for IL12A 抗体 (ABIN498511)
抗原
See all IL12A 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of IL-12A protein. (region surrounding Thr65)
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交叉反应 （详细）
- Species reactivity (expected):Mouse and RatSpecies reactivity (tested):Human.
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纯化方法
- Affinity chromatography
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纯度
- > 95 % by SDS-PAGE
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anti-Interleukin 12 alpha (IL12A) (AA 23-215) antibody
IL12A 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 alpha (IL12A) (AA 23-215) antibodyIL12A 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 alpha (IL12A) (AA 23-219) antibodyIL12A 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 alpha (IL12A) (AA 23-219) antibodyIL12A 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Interleukin 12 alpha (IL12A) (AA 51-150) antibodyIL12A 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), FACS, IHC (fro), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 alpha (IL12A) antibodyMicroarray verified IL12A 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB517533 unconjugated
anti-Interleukin 12 alpha (IL12A) (AA 168-195), (C-Term) antibodyIL12A 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB21410 unconjugated
anti-Interleukin 12 alpha (IL12A) (AA 23-215) antibodyIL12A 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 alpha (IL12A) (AA 144-253) antibodyIL12A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A6 unconjugated
anti-Interleukin 12 alpha (IL12A) (AA 23-219) antibodyIL12A 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- PBS, pH 7.2, 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- IL12A (Interleukin 12 alpha (IL12A))
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别名
- Interleukin-12 alpha / IL12A
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背景
- IL-12 is secreted by macrophages and human B-lymphoblastoid cells in response to antigenic stimulation. This IL is responsible for the differentiation of naive CD4+ T cells into type 1 helper T cells that produce interferon-γ (IFN-γ). It also activates production of tumor necrosis factor α (TNFα) from T and natural killer (NK) cells, and it inhibits IL-4 mediated suppression of IFN-γ. IL-12 also has anti-angiogenic activity since the production of IFN-γ increases the production of inducible protein-10 (IP-10). IL-12 p40 represents a subunit of IL-12 that is induced by several pathogens. IL-12 p70 is a subunit of IL-12 that is controlled through both the p35 and p40 genes in a cell type-specific fashion.Synonyms: CLMF p35, Cytotoxic lymphocyte maturation factor 35 kDa subunit, IL-12 subunit p35, IL-12A, NK cell stimulatory factor chain 1, NKSF1
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分子量
- approx. 25 kDa
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基因ID
- 3592
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NCBI登录号
- NP_000873
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UniProt
- P29459
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途径
- JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
抗原
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