Angiotensin I Converting Enzyme 1 抗体
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- 抗原 See all Angiotensin I Converting Enzyme 1 (ACE) 抗体
- Angiotensin I Converting Enzyme 1 (ACE) (Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Angiotensin I Converting Enzyme 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of BNIP-2 protein. (region surrounding Phe940)
- 交叉反应 (详细)
- Species reactivity (tested):Human, Mouse.
- 纯化方法
- Affinity chromatography
- 纯度
- > 95 % by SDS-PAGE
- Top Product
- Discover our top product ACE Primary Antibody
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- 应用备注
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1,0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- Angiotensin I Converting Enzyme 1 (ACE) (Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))
- 别名
- ACE / CD143 (ACE 产品)
- 别名
- ACE1 antibody, CD143 antibody, DCP antibody, DCP1 antibody, ICH antibody, MVCD3 antibody, AW208573 antibody, Dcp1 antibody, StsRR92 antibody, dcp antibody, ace1 antibody, dcp1 antibody, xace antibody, cd143 antibody, ACE antibody, angiotensin I converting enzyme antibody, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 antibody, angiotensin-converting enzyme antibody, angiotensin I converting enzyme (peptidyl-dipeptidase A) 3 antibody, angiotensin-converting enzyme-like antibody, ACE antibody, Ace antibody, ace antibody, CpipJ_CPIJ009106 antibody, ACE3 antibody, LOC101824864 antibody
- 背景
- The adenovirus E1B protein is a viral homolog of the Bcl-2 family of proteins that are involved in regulating cell death. A family of interacting proteins, which are designated Nip or Bnip and include BNIP-1, BNIP-2, BNIP-3 and Nix, associate with both the E1B protein and Bcl-2 proteins to mediate apoptotic signaling. BNIP-1 contains a hydrophobic transmembrane domain, which enables its localization to the nuclear envelope, endoplasmic recticulum and mitochondria. BNIP-2, (previously designated Nip2 and Nip21 in human and mouse respectively), shares homology with the non-catalytic domain of Cdc42 GTPase-activating protein (Cdc42GAP). Through binding to Cdc42GAP, BNIP-2 enhances the GTPase activity of Cdc42GAP, facilitating the hydrolysis of GTP bound to Cdc42 and thereby, mediating the signaling pathways involving receptor kinases, small GTPases and apoptotic proteins. Nix, which is also designated Nip3L or Bnip3L, is highly related to BNIP-3, and both proteins localize to the mitochondria where they associate with Bcl-2 proteins.Synonyms: Angiotensin-converting enzyme, DCP, DCP1, Dipeptidyl carboxypeptidase I
- 分子量
- approx. 165 kDa
- 基因ID
- 1636
- NCBI登录号
- NP_000780
- UniProt
- P12821
- 途径
- ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration
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