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Laminin gamma 1 抗体

LAMC1 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN498386
发货至: 中国
  • 抗原 See all Laminin gamma 1 (LAMC1) 抗体
    Laminin gamma 1 (LAMC1) (Laminin, gamma 1 (LAMC1))
    适用
    • 46
    • 24
    • 19
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 38
    • 9
    • 5
    克隆类型
    • 37
    • 15
    多克隆
    标记
    • 36
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Laminin gamma 1 antibody is un-conjugated
    应用范围
    • 31
    • 21
    • 16
    • 13
    • 9
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    特异性
    This antibody detects endogenous levels of Laminin gamma-1 protein. (region surrounding Glu1472)
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    Affinity Chromatography using epitope-specific immunogen.
    Top Product
    Discover our top product LAMC1 Primary Antibody
  • 应用备注
    Western Blot: 1/500-1/1000. Immunofluorescence: 1/50-1/200. Immunohistochemistry on Paraffin Sections: 1/50-1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2., 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    Laminin gamma 1 (LAMC1) (Laminin, gamma 1 (LAMC1))
    别名
    Laminin gamma 1 (LAMC1 产品)
    别名
    lamb2 antibody, Lamb2 antibody, B2e antibody, sly antibody, LAMB2 antibody, putative laminin gamma-1 chain antibody, laminin subunit gamma 1 antibody, laminin, gamma 1 antibody, Smp_163810 antibody, lamc1 antibody, Lamc1 antibody, LAMC1 antibody
    背景
    Laminins are essential and abundant structural non-collagenous glycoproteins localizing to basement membranes. Basement membranes (cell-associated extracellular matrices (ECMs)) are polymers of Laminins with stabilizing Type IV Collagen networks, Nidogen and several proteoglycans. Basement membranes are found under epithelial layers, around the endothelium of blood vessels, and surrounding muscle, peripheral nerve and fat cells. Formation of basement membranes influences cell proliferation, phenotype, migration, gene expression and tissue architecture. Each Laminin is a heterotrimer of alpha, beta and gamma chain subunits that undergoes cell-secretion and incorporation into the ECM. Laminins can self-assemble, bind to other matrix macromolecules and have unique and shared cell interactions mediated by Integrins, dystroglycan and cognate Laminin receptors. The human Laminin gamma-1 gene maps to chromosome 1q31 and is ubiquitously expressed in tissues that produce basement membranes.Synonyms: LAMB2, LAMC1, Laminin B2 chain, Laminin subunit gamma-1
    分子量
    approx. 178.0 kDa
    基因ID
    3915
    NCBI登录号
    NP_002284
    UniProt
    P11047
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