LIM Domain Kinase 1 抗体
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Quick Overview for LIM Domain Kinase 1 抗体 (ABIN498284)
抗原
See all LIM Domain Kinase 1 (LIMK1) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of LIMK-1 protein. (region surrounding Gln491)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography
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纯度
- > 95 % by SDS-PAGE
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anti-LIM Domain Kinase 1 (LIMK1) (pThr508) antibody
LIMK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-LIM Domain Kinase 1 (LIMK1) antibodyLIMK1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, IF, IHC (p), FACS 宿主: 小鼠 Monoclonal 3H6 unconjugated
anti-LIM Domain Kinase 1 (LIMK1) antibodyLIMK1 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, IHC, IF, IHC (p), FACS 宿主: 小鼠 Monoclonal 6B4 unconjugated
anti-LIM Domain Kinase 1 (LIMK1) (AA 451-550) antibodyLIMK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-LIM Domain Kinase 1 (LIMK1) (AA 548-647) antibodyLIMK1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A8 unconjugated
anti-LIM Domain Kinase 1 (LIMK1) (AA 548-647) antibodyLIMK1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1B2 unconjugated
anti-LIM Domain Kinase 1 (LIMK1) (AA 548-647) antibodyLIMK1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2E9 unconjugated
anti-LIM Domain Kinase 1 (LIMK1) (AA 1-647) antibodyLIMK1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-LIM Domain Kinase 1 (LIMK1) (pThr508) antibodyLIMK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-LIM Domain Kinase 1 (LIMK1) (pThr508) antibodyLIMK1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- PBS, pH 7.2 containing 0.05 % sodium azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- LIM Domain Kinase 1 (LIMK1)
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别名
- LIMK1
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背景
- There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase 1 and LIM kinase 2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. LIMK1 is likely to be a component of an intracellular signaling pathway and may be involved in brain development. LIMK1 hemizygosity is implicated in the impaired visuospatial constructive cognition of Williams syndrome. Two splice variant have been identified.Synonyms: EC=2.7.11.1, LIM domain kinase 1, LIMK, LIMK-1
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分子量
- approx. 72 kDa
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基因ID
- 3984
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NCBI登录号
- NP_002305
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UniProt
- P53667
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途径
- Caspase Cascade in Apoptosis, Regulation of Cell Size, CXCR4-mediated Signaling Events
抗原
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