STAT1 抗体
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北京 101111
Quick Overview for STAT1 抗体 (ABIN498282)
抗原
See all STAT1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of Stat1 protein. (region surrounding Leu177)
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- Affinity chromatography
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纯度
- > 95 % by SDS-PAGE
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anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (pSer727) antibody
STAT1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 717-745), (C-Term) antibodySTAT1 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB41406 unconjugated
anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 343-602) antibodySTAT1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) antibodyKD Validated STAT1 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 23GB4185 unconjugated Recombinant Antibody
anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 114-143), (N-Term) antibodySTAT1 适用: 人, 小鼠, 大鼠 WB, FACS 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 1-712) antibodySTAT1 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 513-712) antibodySTAT1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 2-230) antibodySTAT1 适用: 人 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 2-230) antibodySTAT1 适用: 人, 猴 WB, IHC, IF, ICC, FACS 宿主: 小鼠 Monoclonal 12C7 unconjugated
anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 613-712) antibodySTAT1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1A8 unconjugated
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应用备注
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- STAT1 (Signal Transducer and Activator of Transcription 1, 91kDa (STAT1))
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别名
- STAT1
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背景
- STATs (signal transducers and activators of transcription) were originally discovered as two proteins (STAT1 and STAT2) which were involved in interferon alpha (IFN alpha) and IFN gamma signal transduction. Since then, several additional STAT proteins have been identified (STAT3, 4, 5,a 5b, and 6). STATs undergo tyrosine phosphorylation in response to growth factor or cytokine signaling. This phosphorylation results in dimerization and translocation of STAT proteins to the nucleus. In some cases this process is mediated by JAK Kinases (Janus Kinases 1, 2, and 3). For maximum activation of these proteins, phosphorylation at specific tyrosine and serine residues may be required in STAT1 alph,a 3, 4, and 5. Specific functions of the STAT proteins are poorly defined at this time. They are thought to be involved in a variety of systems including antiviral responses and cell transformation.Synonyms: Signal transducer and activator of transcription 1-alpha/beta, Transcription factor ISGF-3 components p91/p84
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分子量
- approx. 87 kDa
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基因ID
- 6772
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NCBI登录号
- NP_009330
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UniProt
- P42224
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途径
- JAK/STAT Signaling, RTK signaling, Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Hepatitis C, CXCR4-mediated Signaling Events
抗原
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