NEK9 抗体
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北京 101111
Quick Overview for NEK9 抗体 (ABIN498262)
抗原
See all NEK9 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of Nek9 protein.
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity Chromatography using epitope-specific immunogen.
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anti-NIMA (Never in Mitosis Gene A)- Related Kinase 9 (NEK9) (AA 226-326) antibody
NEK9 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1F6 unconjugated
anti-NIMA (Never in Mitosis Gene A)- Related Kinase 9 (NEK9) antibodyKD Validated NEK9 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 24GB6355 unconjugated
anti-NIMA (Never in Mitosis Gene A)- Related Kinase 9 (NEK9) (AA 730-979) antibodyNEK9 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-NIMA (Never in Mitosis Gene A)- Related Kinase 9 (NEK9) antibodyNEK9 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-NIMA (Never in Mitosis Gene A)- Related Kinase 9 (NEK9) (Internal Region) antibodyNEK9 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-NIMA (Never in Mitosis Gene A)- Related Kinase 9 (NEK9) (AA 821-979) antibodyNEK9 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-NIMA (Never in Mitosis Gene A)- Related Kinase 9 (NEK9) antibodyNEK9 适用: 人, 马, 兔, Pig, 猴, Hamster IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-NIMA (Never in Mitosis Gene A)- Related Kinase 9 (NEK9) (Kinase Domain) antibodyNEK9 适用: 人, 小鼠, 马, 兔, Cow, Pig, 猴, Bat, 小鸡 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-NIMA (Never in Mitosis Gene A)- Related Kinase 9 (NEK9) (AA 846-877), (C-Term) antibodyNEK9 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB2989 unconjugated
anti-NIMA (Never in Mitosis Gene A)- Related Kinase 9 (NEK9) (AA 1-979) antibodyNEK9 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Western blot: 1: 500 - 1: 1000. Immunoflourescence: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- NEK9 (NIMA (Never in Mitosis Gene A)- Related Kinase 9 (NEK9))
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别名
- NEK9
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背景
- Nek8 (also designated never in mitosis A (NimA)-related kinase 8, Jck and NEK12A) is a mitotic regulator that plays a significant role in maintaining renal tubular integrity. Nek8 transcript is abundant in thyroid, adrenal gland and skin, with overexpression in breast tumors and infiltrating ductal carcinomas, and moderate levels in mucinous adenocarcinoma. Nek8 mutations correlate to juvenile autosomal recessive polycystic kidney disease in humans. Nek9 (never in mitosis A (NimA)-related kinase 9, Nercc1 kinase) regulates G1/S transition and S phase progression by influencing spindle dynamics and chromosome separation. Nek9 phosphorylates different histones (Histone H3 on serine and threonine), myelin basic protein, β-casein (serine) and BICD2. Nek9 interacts with Ran GTPase, Nek6, Nek7, BICD2, SSRP1 and SUPT16H/ FACT complex. Nek9 transcript is abundant in heart, liver, kidney and testis. Nek family cell-cycle protein kinases in humans have at least 11 members that share an amino-terminal catalytic domain related to NIMA, an Aspergillus nidulans kinase that plays on several aspects of mitosis, with divergent carboxyl-terminal tails of varying length.Synonyms: KIAA1995, NEK8, NERCC, NIMA-related kinase 8, Nercc1 kinase, Never in mitosis A-related kinase 9
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分子量
- approx. 107.0 kDa
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基因ID
- 91754
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NCBI登录号
- NP_149107
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UniProt
- Q8TD19
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途径
- SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
抗原
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