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ACLY 抗体

ACLY 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN498187
发货至: 中国
  • 抗原 See all ACLY 抗体
    ACLY (ATP Citrate Lyase (ACLY))
    适用
    • 93
    • 41
    • 40
    • 9
    • 6
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 82
    • 13
    克隆类型
    • 72
    • 23
    多克隆
    标记
    • 48
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    This ACLY antibody is un-conjugated
    应用范围
    • 76
    • 33
    • 27
    • 26
    • 15
    • 14
    • 13
    • 12
    • 10
    • 6
    • 4
    • 3
    • 3
    • 2
    Western Blotting (WB), Immunofluorescence (IF)
    特异性
    This antibody detects endogenous levels of ATP-citrate synthase protein.
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    Affinity Chromatography using epitope-specific immunogen.
    Top Product
    Discover our top product ACLY Primary Antibody
  • 应用备注
    Western blot: 1: 500 - 1: 1000. Immunoflourescence: 1: 50 - 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH ~7.2 with 0.05 % Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    ACLY (ATP Citrate Lyase (ACLY))
    别名
    ATP-Citrate Synthase (ACLY 产品)
    别名
    ACLY antibody, DDBDRAFT_0205389 antibody, DDBDRAFT_0235360 antibody, DDB_0205389 antibody, DDB_0235360 antibody, ACL antibody, BcDNA:LD21334 antibody, CG8322 antibody, DmATPCL antibody, Dmel\\CG8322 antibody, anon-WO0140519.179 antibody, dATPCL antibody, l(2)01466 antibody, l(2)k09217 antibody, n(2)k09217 antibody, ATPCL antibody, CLATP antibody, A730098H14Rik antibody, AW538652 antibody, Clatp antibody, acly antibody, cb722 antibody, zgc:92008 antibody, ATP citrate lyase antibody, ATP citrate lyase S homeolog antibody, ATP-citrate synthase antibody, citrate synthase, mitochondrial antibody, atp-citrate synthase antibody, ATP citrate lyase a antibody, ACLY antibody, acly.S antibody, LOC587157 antibody, acly antibody, ATPCL antibody, LOC5564509 antibody, CpipJ_CPIJ010291 antibody, Bm1_26245 antibody, ACL antibody, Acly antibody, aclya antibody
    背景
    ATP citrate lyase (ACL) is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer of four identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. One of these products, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. NDPK has been found to phosphorylate ACL and insulin to increase phosphorylation of ACL.Synonyms: ACLY, ATP citrate (pro-S-)-lyase, Citrate cleavage enzyme
    分子量
    approx. 120 kDa
    基因ID
    47
    NCBI登录号
    NP_001087
    UniProt
    P53396
    途径
    Warburg Effect
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