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CSF1R 抗体

CSF1R 适用: 人, 小鼠, 大鼠 IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN498117
发货至: 中国
  • 抗原 See all CSF1R 抗体
    CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))
    适用
    • 192
    • 135
    • 97
    • 17
    • 8
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 224
    • 20
    • 9
    • 3
    • 2
    克隆类型
    • 226
    • 31
    • 1
    多克隆
    标记
    • 93
    • 27
    • 15
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    • 13
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 5
    • 5
    • 5
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CSF1R antibody is un-conjugated
    应用范围
    • 174
    • 106
    • 81
    • 67
    • 50
    • 26
    • 24
    • 20
    • 12
    • 6
    • 5
    • 4
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    • 1
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    Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of CSFR protein.
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    Affinity Chromatography using epitope-specific immunogen.
    Top Product
    Discover our top product CSF1R Primary Antibody
  • 应用备注
    Immunoflourescence: 1/50-1/200. Immunohistochemistry on Paraffin Sections: 1/50-1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Dekker, van Geemen, van den Bogaerdt, Driessen-Mol, Aikawa, Smits: "Sheep-Specific Immunohistochemical Panel for the Evaluation of Regenerative and Inflammatory Processes in Tissue-Engineered Heart Valves." in: Frontiers in cardiovascular medicine, Vol. 5, pp. 105, (2018) (PubMed).

  • 抗原
    CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))
    别名
    CD115 (CSF1R 产品)
    别名
    AI323359 antibody, CD115 antibody, CSF-1R antibody, Csfmr antibody, Fim-2 antibody, Fms antibody, M-CSF-R antibody, M-CSFR antibody, C-FMS antibody, CSFR antibody, FIM2 antibody, FMS antibody, HDLS antibody, PDGFRB antibody, MGC89146 antibody, CSF-1-R antibody, c-fms antibody, mrfms antibody, CSF1 antibody, M-CSF antibody, csf1r antibody, fms antibody, panther antibody, colony stimulating factor 1 receptor antibody, macrophage colony-stimulating factor receptor antibody, colony stimulating factor 1 receptor, a antibody, Csf1r antibody, CSF1R antibody, m-csfr antibody, csf1r antibody, csf1ra antibody
    背景
    This protein tyrosine kinase transmembrane receptor is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a member of the CSF1/PDGF receptor family of tyrosine protein kinases and contains 5 immunoglobulin like C2 type domains. CD115 is expressed by cells of the monocytic lineage and by progenitor cells. Mutations in this gene have been associated with a predisposition to myeloid malignancy.Synonyms: CSF-1-R, CSF1R, FMS, Fms proto-oncogene, Macrophage colony-stimulating factor 1 receptor, c-fms
    分子量
    approx. 92, 108 kDa
    基因ID
    1436
    NCBI登录号
    NP_005202
    UniProt
    P07333
    途径
    RTK signaling, Inositol Metabolic Process, Cell-Cell Junction Organization
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