ATG3 抗体 (Middle Region)
Our Local Distributor
北京 101111
Quick Overview for ATG3 抗体 (Middle Region) (ABIN497989)
抗原
See all ATG3 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Middle Region
-
纯化方法
- Immunoaffinity Chromatography
-
免疫原
- ATG3 antibody was raised against an 18 amino acid peptide near the center of Human ATG3 (GenBank accession no. NP_071933).
-
亚型
- IgG
-
-
-
-
应用备注
-
ELISA. Western blot: ATG3 antibody can be used for the detection of ATG3 at 1-2 μg/mL. Positive Control: Mouse Kidney Tissue Lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- -20 °C
-
储存方法
- Store the antibody (in aliquots) at -20 °C.
-
-
- ATG3 (ATG3 Autophagy Related 3 (ATG3))
-
别名
- APG3 / ATG3
-
背景
- Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1. ATG3 (APG3) is a widely expressed conjugating enzyme for APG8 lipidation, an essential step for the initiation of autophagy. It functions as an E2-like enzyme during the initial stages of autophagosome formation by catalyzing the formation of the Atg8-phosphatidylethanolamine (Atg8-PE) conjugate, which is critical for autophagy.Synonyms: APG3-like, APG3L, Autophagy-related protein 3, Protein PC3-96
-
基因ID
- 64422
-
NCBI登录号
- NP_071933
-
UniProt
- Q9NT62
-
途径
- Autophagy
抗原
-