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VEGFA 抗体 (AA 140-168)

This anti-VEGFA antibody is a 兔 多克隆 antibody detecting VEGFA in WB 和 ELISA. Suitable for 人.
产品编号 ABIN3029575
发货至: 中国

Quick Overview for VEGFA 抗体 (AA 140-168) (ABIN3029575)

抗原

See all VEGFA 抗体
VEGFA (Vascular Endothelial Growth Factor A (VEGFA))

适用

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宿主

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克隆类型

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  • 86
  • 2
多克隆

标记

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This VEGFA antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 140-168

    纯化方法

    Antigen affinity purified

    免疫原

    A portion of amino acids 140-168 from the human protein was used as the immunogen for this VEGF-A antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the VEGF-A antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the VEGF-A antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    VEGFA (Vascular Endothelial Growth Factor A (VEGFA))

    别名

    VEGF-A

    背景

    This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms.

    UniProt

    P15692

    途径

    RTK signaling, Glycosaminoglycan Metabolic Process, Regulation of Cell Size, Tube Formation, Signaling Events mediated by VEGFR1 and VEGFR2, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling
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