p63 抗体 (AA 651-680)
Our Local Distributor
北京 101111
Quick Overview for p63 抗体 (AA 651-680) (ABIN3029399)
抗原
See all p63 (TP63) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 651-680
-
纯化方法
- Antigen affinity purified
-
免疫原
- A portion of amino acids 651-680 from the human protein was used as the immunogen for this TP63 antibody.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- Titration of the TP63 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Aliquot the TP63 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
-
- p63 (TP63) (Tumor Protein P63 (TP63))
-
别名
- TP63
-
背景
- This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3), split-hand/foot malformation 4 (SHFM4), ankyloblepharon-ectodermal defects-cleft lip/palate, ADULT syndrome (acro-dermato-ungual-lacrimal-tooth), limb-mammary syndrome, Rap-Hodgkin syndrome (RHS), and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined.
-
UniProt
- Q9H3D4
抗原
-