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TLR3 抗体

TLR3 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3029166
发货至: 中国
  • 抗原 See all TLR3 抗体
    TLR3 (Toll-Like Receptor 3 (TLR3))
    适用
    • 98
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    宿主
    • 85
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    克隆类型
    • 88
    • 33
    多克隆
    标记
    • 53
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    This TLR3 antibody is un-conjugated
    应用范围
    • 84
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    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    纯化方法
    Antigen affinity purified
    免疫原
    This TLR3 antibody was produced from rabbits immunized with TLR3 recombinant protein.
    亚型
    Ig Fraction
    Top Product
    Discover our top product TLR3 Primary Antibody
  • 应用备注
    Titration of the TLR3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In 1X PBS pH 7.4 with 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot the TLR3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原
    TLR3 (Toll-Like Receptor 3 (TLR3))
    别名
    TLR3 (TLR3 产品)
    别名
    CD283 antibody, IIAE2 antibody, AI957183 antibody, zgc:123006 antibody, toll like receptor 3 antibody, toll-like receptor 3 antibody, TLR3 antibody, Tlr3 antibody, tlr3 antibody
    背景
    The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. It may thus play a role in host defense against viruses. Use of alternative polyadenylation sites to generate different length transcripts has been noted for this gene.
    UniProt
    O15455
    途径
    TLR signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
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