TLR2 抗体 (AA 212-242)
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Quick Overview for TLR2 抗体 (AA 212-242) (ABIN3029164)
抗原
See all TLR2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 212-242
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交叉反应 （详细）
- Expected species reactivity: Primate
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纯化方法
- Purified
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免疫原
- A portion of amino acids 212-242 from the human protein was used as the immunogen for this TLR2 antibody.
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亚型
- Ig Fraction
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anti-Toll-Like Receptor 2 (TLR2) (AA 720-749) antibody
TLR2 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 2 (TLR2) antibodyTLR2 适用: 人 WB 宿主: 小鼠 Monoclonal 1070CT4-2-3-2 unconjugated
anti-Toll-Like Receptor 2 (TLR2) (AA 281-310) antibodyTLR2 适用: 人 WB 宿主: 兔 Polyclonal RB33608 unconjugated
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应用备注
- Titration of the TLR2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the TLR2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- TLR2 (Toll-Like Receptor 2 (TLR2))
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别名
- TLR2
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背景
- TLR2 cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR6. [UniProt]
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UniProt
- O60603
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途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades
抗原
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