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TLR2 抗体 (C-Term)

TLR2 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2800624
发货至: 中国
  • 抗原 See all TLR2 抗体
    TLR2 (Toll-Like Receptor 2 (TLR2))
    抗原表位
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 720-749, C-Term
    适用
    • 15
    • 6
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 13
    • 8
    克隆类型
    • 13
    • 8
    多克隆
    标记
    • 16
    • 2
    • 2
    • 1
    This TLR2 antibody is un-conjugated
    应用范围
    • 10
    • 10
    • 9
    • 6
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    原理
    Rabbit Anti-Mouse TLR2 (C-term) Antibody
    免疫原
    This Mouse TLR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 720-749 amino acids from the C-terminal region of mouse TLR2.
    亚型
    Ig Fraction
    Top Product
    Discover our top product TLR2 Primary Antibody
  • 应用备注
    Western Blot, Immunohistochemistry
    Recommended Dilutions
    WB: 1:1000, IHC: 1:50-100Western blot analysis of anti-TLR2 Pab (102-12774) pre-incubated without and with blocking peptide (BP#1502c) in CEM cell line lysate. TLR2-V735(arrow) was detected using the purified Pab.
    Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated. BC = breast carcinoma, HC = hepatocarcinoma.
    Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with Mouse Tlr2 antibody (N-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    2.0 mg/mL
    储存条件
    4 °C,-20 °C
    储存方法
    2-8°C (short-term), -20°C (long-term)
  • 抗原
    TLR2 (Toll-Like Receptor 2 (TLR2))
    别名
    TLR2 (TLR2 产品)
    别名
    CD282 antibody, TIL4 antibody, Ly105 antibody, toll like receptor 2 antibody, toll-like receptor 2 antibody, TLR2 antibody, Tlr2 antibody, tlr2 antibody
    背景

    Target Description: TLR2 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. TLR2 is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.

    Gene Symbol: Tlr2

    分子量
    89449 Da
    基因ID
    24088
    UniProt
    Q9QUN7
    途径
    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades
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