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MAPT 抗体 (AA 677-707)

The 兔 多克隆 anti-MAPT antibody is suitable to detect MAPT in samples from 人. It has been validated for WB, ELISA, IHC 和 IF.
产品编号 ABIN3031796
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MAPT 抗体 (AA 677-707) (ABIN3031796)

抗原

See all MAPT 抗体
MAPT (Microtubule-Associated Protein tau (MAPT))

适用

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宿主

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克隆类型

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多克隆

标记

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This MAPT antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    AA 677-707

    原理

    TAU Antibody / MAPT

    交叉反应 (详细)

    Expected species reactivity: Mouse, Rat, Bovine

    纯化方法

    Purified

    免疫原

    A portion of amino acids 677-707 from the human protein was used as the immunogen for this TAU antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the TAU antibody may be required due to differences in protocols and secondary/substrate sensitivity.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the TAU antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    MAPT (Microtubule-Associated Protein tau (MAPT))

    别名

    TAU

    背景

    TAU/MAPT promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. [UniProt]

    UniProt

    P10636

    途径

    MAPK Pathway, Microtubule Dynamics, M Phase, Regulation of Cell Size
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