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SYK 抗体 (AA 195-223)

This anti-SYK antibody is a 兔 多克隆 antibody detecting SYK in WB 和 ELISA. Suitable for 人 和 小鼠.
产品编号 ABIN3032716
发货至: 中国

Quick Overview for SYK 抗体 (AA 195-223) (ABIN3032716)

抗原

See all SYK 抗体
SYK (Spleen tyrosine Kinase (SYK))

适用

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人, 小鼠

宿主

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克隆类型

  • 160
  • 15
多克隆

标记

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This SYK antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 195-223

    交叉反应 (详细)

    Expected species reactivity: Chicken, Rat

    纯化方法

    Antigen affinity purified

    免疫原

    A portion of amino acids 195-223 from the mouse protein was used as the immunogen for this Syk antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the Syk antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the Syk antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    SYK (Spleen tyrosine Kinase (SYK))

    别名

    Syk

    背景

    Positive effector of BCR-stimulated responses. Couples the B-cell antigen receptor (BCR) to the mobilization of calcium ion either through a phosphoinositide 3-kinase-dependent pathway, when not phosphorylated on tyrosines of the linker region, or through a phospholipase C-gamma-dependent pathway, when phosphorylated on Tyr-342 and Tyr-346. Thus the differential phosphorylation of Syk can determine the pathway by which BCR is coupled to the regulation of intracellular calcium ion. Phosphorylates USP25 and regulates its intracellular levels (By similarity).

    UniProt

    P48025

    途径

    Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Thromboxane A2 Receptor Signaling, BCR Signaling
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