Src 抗体 (AA 98-125)
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Quick Overview for Src 抗体 (AA 98-125) (ABIN3029551)
抗原
See all Src 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 98-125
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 98-125 from the mouse protein was used as the immunogen for this Src antibody.
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亚型
- Ig Fraction
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anti-Proto-oncogene tyrosine-protein kinase Src (Src) antibody
Src 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 1F11 unconjugated
anti-Proto-oncogene tyrosine-protein kinase Src (Src) (pTyr530) antibodySrc 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Proto-oncogene tyrosine-protein kinase Src (Src) antibodySrc 适用: 人, 小鼠 WB, IF 宿主: 小鼠 Monoclonal 17AT28 unconjugated
anti-Proto-oncogene tyrosine-protein kinase Src (Src) (AA 24-52), (N-Term) antibodySrc 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB41141 unconjugated
anti-Proto-oncogene tyrosine-protein kinase Src (Src) antibodyKO Validated Src 适用: 人 WB, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Proto-oncogene tyrosine-protein kinase Src (Src) (AA 24-52) antibodySrc 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Proto-oncogene tyrosine-protein kinase Src (Src) (AA 397-424) antibodySrc 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Proto-oncogene tyrosine-protein kinase Src (Src) (pTyr529) antibodySrc 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Proto-oncogene tyrosine-protein kinase Src (Src) (pTyr419) antibodySrc 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Proto-oncogene tyrosine-protein kinase Src (Src) (AA 1-90) antibodySrc 适用: 人 WB, ELISA, IF, IHC (p), PLA 宿主: 小鼠 Monoclonal 1B9 unconjugated
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应用备注
- Titration of the Src antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Src antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Src (Proto-oncogene tyrosine-protein kinase Src (Src))
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别名
- Src
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背景
- Non-receptor protein tyrosine kinase that plays pivotal roles in numerous cellular processes such as proliferation, migration, and transformation. In concert with PTK2B, plays an important role in osteoclastic bone resorption. Both the formation of a SRC-PTK2B complex, and SRC kinase activity are necessary for this function. Once it is recruited to the activated integrins, by PTK2B, it phosphorylates CBL which in turn induces the activation and recruitment of phosphatidylinositol 3-kinase to the cell membrane in a signaling pathway that is critical for osteoclast function. Promotes energy production in osteoclasts by activating mitochondrial cytochrome C oxidase. Phosphorylates RUNX3 and COX2 on tyrosine residues, TNK2 on 'Tyr-284' and CBL on 'Tyr-731'. Enhances DDX58/RIG-I-elicited antiviral signaling.
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UniProt
- P05480
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途径
- JAK/STAT Signaling, Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling, Platelet-derived growth Factor Receptor Signaling, Thromboxane A2 Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
抗原
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