Sonic Hedgehog 抗体 (AA 395-450)
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Quick Overview for Sonic Hedgehog 抗体 (AA 395-450) (ABIN3029025)
抗原
See all Sonic Hedgehog (SHH) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 395-450
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原理
- Shh Antibody / Sonic Hedgehog
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纯化方法
- Antigen affinity
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免疫原
- A portion of amino acids 395-450 were used as immunogen for this Shh antibody.
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亚型
- Ig Fraction
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应用备注
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Titration of the Shh antibody may be required due to differences in protocols and secondary/substrate sensitivity.
1. The 45 kDa precursor protein autocleaves into 27 kDa amino and 19 kDa carboxy fragments.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Shh antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Sonic Hedgehog (SHH)
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别名
- Shh
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背景
- Sonic hedgehog binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. In the absence of SHH, PTC represses the constitutive signaling activity of SMO.
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UniProt
- Q62226
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途径
- Hedgehog Signaling, Dopaminergic Neurogenesis, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
抗原
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