Rhodopsin 抗体 (AA 310-339)
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Quick Overview for Rhodopsin 抗体 (AA 310-339) (ABIN3032473)
抗原
See all Rhodopsin (RHO) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 310-339
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交叉反应 (详细)
- Expected species reactivity: Primate
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 310-339 from human Rhodopsin was used as the immunogen for this RHO antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the RHO antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the RHO antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Rhodopsin (RHO)
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别名
- rho (Rhodopsin)
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物质类
- Chemical
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背景
- Retinitis pigmentosa is an inherited progressive disease which is a major cause of blindness in western communities. It can be inherited as an autosomal dominant, autosomal recessive, or X-linked recessive disorder. In the autosomal dominant form,which comprises about 25 % of total cases, approximately 30 % of families have mutations in the gene encoding the rod photoreceptor-specific protein rhodopsin. This is the transmembrane protein which, when photoexcited, initiates the visual transduction cascade. Defects in this gene are also one of the causes of congenital stationary night blindness.
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UniProt
- P08100
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途径
- WNT signaling, Sensory Perception of Sound, Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
抗原
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