Retinoblastoma Protein (Rb) 抗体 (AA 858-886)
Quick Overview for Retinoblastoma Protein (Rb) 抗体 (AA 858-886) (ABIN3029813)
抗原
See all Retinoblastoma Protein (Rb) (Rb Protein) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 858-886
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交叉反应 (详细)
- Expected species reactivity: Rat
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纯化方法
- Purified
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免疫原
- A portion of amino acids 858-886 from the human protein was used as the immunogen for this Retinoblastoma antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the Retinoblastoma antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Retinoblastoma antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))
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别名
- Retinoblastoma
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背景
- RB1/Retinoblastoma is a negative regulator of the cell cycle and was the first tumor suppressor gene found. This protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1.
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UniProt
- P06400
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途径
- Mitotic G1-G1/S Phases
抗原
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