Ret Proto-Oncogene 抗体 (AA 1012-1042)
Quick Overview for Ret Proto-Oncogene 抗体 (AA 1012-1042) (ABIN3032460)
抗原
See all Ret Proto-Oncogene (RET) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1012-1042
-
纯化方法
- Purified
-
免疫原
- A portion of amino acids 1012-1042 from the human protein was used as the immunogen for this RET antibody.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- Titration of the RET antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Aliquot the RET antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
-
- Ret Proto-Oncogene (RET)
-
别名
- RET
-
背景
- RET, a member of the cadherin superfamily, is one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This protein plays a crucial role in neural crest development, and the gene can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations i are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma.
-
UniProt
- P07949
-
途径
- RTK signaling, Dopaminergic Neurogenesis, Regulation of Cell Size, Tube Formation
抗原
-