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Retinoblastoma Protein (Rb) 抗体 (AA 586-615)

This anti-Retinoblastoma Protein (Rb) antibody is a 兔 多克隆 antibody detecting Retinoblastoma Protein (Rb) in WB, ELISA, IHC 和 IF. Suitable for 人.
产品编号 ABIN3032465
发货至: 中国

Quick Overview for Retinoblastoma Protein (Rb) 抗体 (AA 586-615) (ABIN3032465)

抗原

See all Retinoblastoma Protein (Rb) (Rb Protein) 抗体
Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))

适用

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宿主

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克隆类型

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多克隆

标记

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This Retinoblastoma Protein (Rb) antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
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    AA 586-615

    纯化方法

    Antigen affinity purified

    免疫原

    A portion of amino acids 586-615 from the human protein was used as the immunogen for this Rb antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the Rb antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:10-1:50,IHC (Paraffin): 1:10-1:50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the Rb antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))

    别名

    Rb (Retinoblastoma)

    背景

    The retinoblastoma protein is a tumor suppressor protein that is dysfunctional in many types of cancer. One highly studied function of pRb is to prevent excessive cell growth by inhibiting cell cycle progression until a cell is ready to divide. pRb belongs to the pocket protein family, whose members have a pocket for the functional binding of other proteins. Should an oncogenic protein, such as those produced by cells infected by high-risk types of human papillomaviruses, bind and inactivate pRb, this can lead to cancer. Retinoblastoma (Rb) is an embryonic malignant neoplasm of retinal origin. It almost always presents in early childhood and is often bilateral.

    UniProt

    P06400

    途径

    Mitotic G1-G1/S Phases
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