PKC alpha 抗体 (AA 299-329)
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Quick Overview for PKC alpha 抗体 (AA 299-329) (ABIN3032373)
抗原
See all PKC alpha (PKCa) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 299-329
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交叉反应 （详细）
- Expected species reactivity: Mouse, Rat, Rabbit
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纯化方法
- Purified
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免疫原
- A portion of amino acids 299-329 from the human protein was used as the immunogen for this PKC alpha antibody.
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亚型
- Ig Fraction
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anti-Protein Kinase C, alpha (PKCa) antibody
KD Validated PKCa 适用: 人 WB, ICC, FACS, IF (p) 宿主: 兔 Monoclonal 23GB1690 unconjugated Recombinant Antibody
anti-Protein Kinase C, alpha (PKCa) (AA 563-672) antibodyPKCa 适用: 人 WB, ELISA, IF, IHC (p), PLA 宿主: 小鼠 Monoclonal 2F11 unconjugated
anti-Protein Kinase C, alpha (PKCa) (pThr638) antibodyPKCa 适用: 人, 小鼠 WB, IHC (p), FACS, IF (cc) 宿主: 兔 Monoclonal 4B3 unconjugated
anti-Protein Kinase C, alpha (PKCa) (pThr638) antibodyPKCa 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, alpha (PKCa) (pSer657) antibodyKD Validated PKCa 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB1055 unconjugated Recombinant Antibody
anti-Protein Kinase C, alpha (PKCa) (AA 299-329), (C-Term) antibodyPKCa 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB01012 unconjugated
anti-Protein Kinase C, alpha (PKCa) antibodyPKCa 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated
anti-Protein Kinase C, alpha (PKCa) (C-Term) antibodyPKCa 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, alpha (PKCa) antibodyKD Validated PKCa 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 24GB4475 unconjugated Recombinant Antibody
anti-Protein Kinase C, alpha (PKCa) (pThr638) antibodyKD Validated PKCa 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB4470 unconjugated Recombinant Antibody
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应用备注
- Titration of the PKC alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1:10-1:50,Flow Cytometry: 1:10-1:50,Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the PKC alpha antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- PKC alpha (PKCa) (Protein Kinase C, alpha (PKCa))
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别名
- PKC alpha
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背景
- Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. PKC alpha is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes.
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UniProt
- P17252
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途径
- WNT signaling, TCR Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling
抗原
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