Src 抗体 (pTyr215)
Our Local Distributor
北京 101111
Quick Overview for Src 抗体 (pTyr215) (ABIN3029558)
抗原
See all Src 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- pTyr215
-
交叉反应 (详细)
- Expected species reactivity: Chicken, Mouse, Rat, Xenopus, Zebrafish
-
纯化方法
- Antigen affinity purified
-
免疫原
- This phospho-Src antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pY215 of human Src.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- Titration of the phospho-Src antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Aliquot the phospho-Src antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
-
- Src (Proto-oncogene tyrosine-protein kinase Src (Src))
-
别名
- Src
-
背景
- This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-Src kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. Transcript Variant: This variant (1) represents the longer transcript. Both isoforms 1 and 2 encode the same protein.
-
UniProt
- P12931
-
途径
- JAK/STAT Signaling, Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling, Platelet-derived growth Factor Receptor Signaling, Thromboxane A2 Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
抗原
-