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CDKN1B 抗体 (pThr170)

This anti-CDKN1B antibody is a 兔 多克隆 antibody detecting CDKN1B in ELISA 和 DB. Suitable for 人.
产品编号 ABIN3030632
发货至: 中国

Quick Overview for CDKN1B 抗体 (pThr170) (ABIN3030632)

抗原

See all CDKN1B 抗体
CDKN1B (Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B))

适用

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宿主

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克隆类型

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多克隆

标记

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This CDKN1B antibody is un-conjugated

应用范围

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ELISA, Dot Blot (DB)
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    pThr170

    交叉反应 (详细)

    Expected species reactivity: Mouse, Hamster

    纯化方法

    Antigen affinity purified

    免疫原

    This phospho-p27Kip1 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pT170 of human p27Kip1.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the phospho-p27Kip1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Dot blot: 1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the phospho-p27Kip1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    CDKN1B (Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B))

    别名

    p27KIP1

    背景

    This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. [provided by RefSeq].

    UniProt

    P46527

    途径

    Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Sensory Perception of Sound, Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Synthesis of DNA, Autophagy
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