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CDK2 抗体 (pThr14)

This anti-CDK2 antibody is a 兔 多克隆 antibody detecting CDK2 in ELISA 和 DB. Suitable for 人.
产品编号 ABIN3030608
发货至: 中国

Quick Overview for CDK2 抗体 (pThr14) (ABIN3030608)

抗原

See all CDK2 抗体
CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

适用

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宿主

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克隆类型

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多克隆

标记

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This CDK2 antibody is un-conjugated

应用范围

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ELISA, Dot Blot (DB)
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    pThr14

    交叉反应 (详细)

    Expected species reactivity: Mouse, Rat, Bovine, Hamster, Xenopus

    纯化方法

    Antigen affinity purified

    免疫原

    This phospho-CDK2 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pT14 of human CDK2.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the phospho-CDK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Dot blot: 1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the phospho-CDK2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

    别名

    Cdk2

    背景

    CDK2 is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation.

    UniProt

    P24941

    途径

    PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
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