PDK4 抗体
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北京 101111
Quick Overview for PDK4 抗体 (ABIN3028962)
抗原
See all PDK4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Purified
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免疫原
- A purified His-tagged recombinant protein fragment was used to produced this monoclonal PDK4 antibody.
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亚型
- IgG1
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应用备注
- Titration of the PDK4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the PDK4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))
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别名
- PDK4
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背景
- This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin.
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UniProt
- Q16654
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途径
- PI3K-Akt Signaling, Hedgehog Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
抗原
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