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PAK4 抗体 (AA 187-216)

This anti-PAK4 antibody is a 兔 多克隆 antibody detecting PAK4 in WB, ELISA 和 FACS. Suitable for 人 和 小鼠.
产品编号 ABIN3032118
发货至: 中国

Quick Overview for PAK4 抗体 (AA 187-216) (ABIN3032118)

抗原

See all PAK4 抗体
PAK4 (P21-Activated Kinase 4 (PAK4))

适用

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人, 小鼠

宿主

  • 68
  • 6
  • 1

克隆类型

  • 67
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多克隆

标记

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This PAK4 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • 抗原表位

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    AA 187-216

    纯化方法

    Antigen affinity purified

    免疫原

    A portion of amino acids 187-216 from the mouse protein was used as the immunogen for this Pak4 antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the Pak4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the Pak4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    PAK4 (P21-Activated Kinase 4 (PAK4))

    别名

    Pak4

    背景

    Pak4 activates the JNK pathway. Plays a role in the reorganization of the actin cytoskeleton and in the formation of filopodia. Phosphorylates and inactivates the protein phosphatase SSH1, leading to increased inhibitory phosphorylation of the actin binding/depolymerizing factor cofilin. Decreased cofilin activity may lead to stabilization of actin filaments. Phosphorylates ARHGEF2 (By similarity).

    UniProt

    Q8BTW9

    途径

    RTK signaling
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