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PAK4 抗体 (AA 156-187)

This 兔 多克隆 anti-PAK4 antibody specifically detects PAK4 in WB, ELISA 和 IHC. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN3032119
发货至: 中国
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Room 801-803
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Quick Overview for PAK4 抗体 (AA 156-187) (ABIN3032119)

抗原

See all PAK4 抗体
PAK4 (P21-Activated Kinase 4 (PAK4))

适用

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  • 25
  • 5
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人, 小鼠

宿主

  • 70
  • 5
  • 1

克隆类型

  • 68
  • 8
多克隆

标记

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This PAK4 antibody is un-conjugated

应用范围

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  • 5
  • 2
  • 1
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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 16
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    • 3
    • 3
    • 3
    • 3
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    • 1
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    • 1
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    AA 156-187

    纯化方法

    Purified

    免疫原

    A portion of amino acids 156-187 from the human protein was used as the immunogen for this PAK4 antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the PAK4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:10-1:50,Western blot: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the PAK4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    PAK4 (P21-Activated Kinase 4 (PAK4))

    别名

    PAK4

    背景

    PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3, PAK4, PAK5, and PAK6. PAK proteins serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton.

    UniProt

    O96013

    途径

    RTK signaling
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