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PAK3 抗体 (AA 218-247)

The 兔 多克隆 anti-PAK3 antibody (ABIN3032142) specifically detects PAK3 in WB, ELISA 和 IHC. The antibody is reactive with 人 samples.
产品编号 ABIN3032142
发货至: 中国
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Quick Overview for PAK3 抗体 (AA 218-247) (ABIN3032142)

抗原

See all PAK3 抗体
PAK3

适用

  • 85
  • 41
  • 30
  • 3

宿主

  • 80
  • 5
  • 2

克隆类型

  • 70
  • 18
多克隆

标记

  • 37
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  • 3
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  • 3
  • 2
  • 2
  • 1
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  • 1
  • 1
  • 1
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This PAK3 antibody is un-conjugated

应用范围

  • 68
  • 38
  • 36
  • 13
  • 13
  • 12
  • 11
  • 8
  • 7
  • 3
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  • 1
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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 17
    • 8
    • 7
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    • 3
    • 3
    • 2
    • 2
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    AA 218-247

    纯化方法

    Purified

    免疫原

    A portion of amino acids 218-247 from the human protein was used as the immunogen for this PAK3 antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the PAK3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the PAK3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    PAK3

    别名

    PAK3

    背景

    PAK3, a member of the STE20 subfamily of Ser/Thr protein kinases, acts on a variety of targets. PAK3 interacts tightly with GTP-bound but not GDP-bound CDC42/p21 and RAC1. It shows highly specific binding to the SH3 domains of phospholipase C-gamma and of adapter protein NCK. This protein is highly expressed in postmitotic neurons of the developing and postnatal cerebral cortex and hippocampus. PAK3 is autophosphorylated when activated by CDC42/p21. Defects in PAK3 are the cause of non-specific X-linked nonsyndromic mental retardation type 30 (MRX30). The protein structure contains 1 CRIB domain.

    UniProt

    O75914
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