CDKN1B 抗体 (AA 175-197)
Quick Overview for CDKN1B 抗体 (AA 175-197) (ABIN3030625)
抗原
See all CDKN1B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 175-197
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 175-197 from the mouse protein was used as the immunogen for this p27Kip1 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the p27Kip1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the p27Kip1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- CDKN1B (Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B))
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别名
- p27Kip1
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背景
- Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E-and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of cyclin D-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry.
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UniProt
- P46414
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途径
- Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Sensory Perception of Sound, Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Synthesis of DNA, Autophagy
抗原
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